Native Human Myeloperoxidase

Molecule:

MPO

Synonyms:

MPO

Species:

Human

Cat. No.:

CS230B pdf (datasheet)

Quantity/Size:

2.0 mg

Price:

$1,480.00 BUY

Description:

Myeloperoxidase purified from leucocytes of purulent human sputum which is >98 percent pure. It is a lysosomal protein stored in azurophilic granules of the neutrophil which produces hypochlorous acid from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. Supplied as a lyophilized, salt-free, green soluble powder which is stable for over a year when stored at 5οΨΑ C. 150-160 units per mg of protein. 1 unit will decompose 1 umole of H2O2 per minute at pH 7.0 and 25οΨΑ C using 4-amino-antipyrine as hydrogen donor. Recommended assay buffer: 0.1 M KPO4; pH 7.0 Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of two light chains and two heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.

Entrez Symbol:

MPO

Data PDF:

CS230

Source:

Human sputum

Molecular Weight:

59 kDa reduced

Physical State:

Lyophilized

Formulation:

Salt free Lyophilized powder

Purity:

>95% by SDS-PAGE analysis

Storage/Stability:

When stored at 4οΨΑC, product is stable for 12 months from date of delivery.