Native Human Neutrophil Elastase Lyophilized

Molecule:

ELANE

Species:

Human

Cat. No.:

CRN115AL pdf (datasheet)

Quantity/Size:

100 μg

Price:

$325.00 BUY

Description:

Human Neutrophils, also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. Human Neutrophil(s), have a multilobed nucleus and neutrophilic granules. Neutrophil(s) are phagocytes and have an important role in engulfing and killing extracellular pathogens. The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains. Neutrophil elastase (NE) is a key enzyme for tissue injury caused by activated neutrophils, such as occurs in Acute Lung injury. Human Neutrophil elastase research: Association of plasma neutrophil elastase levels with other inflammatory mediators and clinical features in adult patients with moderate and severe pneumonia. Neutrophil elastase and cancer.

Data PDF:

CRN115AL

Source:

Human Neutrophils

Physical State:

Lyophilized

Formulation:

Lyophilized from 50 mM acetate buffer, pH 5.5

Purity:

>96% by SDS-PAGE

Specific Activity:

10 U/mg protein (Coomassie). One unit will hydrolyze one micromole of Methoxy succinyl-alanine-alanine-proline-valine-p-nitroanilide per minute at 37οΨΑC and pH 7.5.

Reconstitution:

> 1 mg protein/ml in a buffer such as tris buffered saline, pH 7.5. Further dilutions should include a carrier such as 1% BSA.

Storage/Stability:

Stable for 2 years.