Native Human Urokinase

Molecule:

Urokinase

Synonyms:

UPA, uPA, URK, ATF, UPAM, QPD, Abbokinase

Species:

Human

Cat. No.:

CNH019C pdf (datasheet)

Quantity/Size:

25 mg

Price:

$1,035.00 BUY

Description:

Urokinase Plasminogen Activator (uPA) is a secreted serine protease that converts plasminogen to plasmin. Urokinase pre-protein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor (uPAR). Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease.

Entrez Symbol:

PLAU

Data PDF:

CNH019

Source:

Human urine

Molecular Weight:

> 90% High Molecular Weight Urokinase (54 kDa)

Biological Activity:

> 5,000 IU/mg

Specific Activity:

> 70,000 IU/mg protein

Storage/Stability:

Lyophilized product is stable at 2-8°C for up to 2 years.