Rabbit Anti-Human C3a Receptor 1 pAb

Molecule:

C3aR1

Synonyms:

C3AR1, complement C3a receptor 1, AZ3B, C3AR, HNFAG09

Species:

Human

Cat. No.:

CPC000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Rabbit Anti-Human C3a Receptor polyclonal antibody
Background: C3a is an anaphylatoxin generated through activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains. The loop can be readily detected using the rabbit anti-C3a receptor antibody.

Entrez Symbol:

C3aR1

Uniprot Name:

C3AR_HUMAN

Uniprot ID:

Q16581

Data PDF:

CPC000

Specificity:

Recognizes both natural and recombinant Human C3a

Host Species:

Rabbit

Immunogen:

Recombinant Human C3a receptor fragment (amino acids 161-332, corresponding to its second extracellular loop)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl of sterile, distilled water to the vial to fully solubilize the antibody to a concentration of 1 mg/ml.

Application:

FC, IHC

Application notes:

Flow Cytometry: Suggested working dilution of 1:100
Immunohistochemistry: Suggested working dilution of 1:100

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.