Rabbit Anti-Human MKK3/MAP2K3 pAb

Molecule:

MKK3

Synonyms:

MAP2K3, mitogen-activated protein kinase kinase 3, MEK3, MKK3, MAPKK3, PRKMK3, SAPKK2, SAPKK-2

Species:

Human

Cat. No.:

CPM500 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$260.00 BUY

Description:

Rabbit Anti-Human MKK3 Polyclonal Antibody
Background: MKK3 is a protein kinase that phosphorylates the p38 MAPK but not ERK MAPK. Phosphorylation by MKK3 occurs on threonine and tyrosine residues and increases the activity of p38 to stimulate transcription factors ATF2 and Elk-1. MKK3, together with MKK6, serve as upstream regulators of p38 MAPK activation. A structural variant, MKK3b, has been identified that contains 29 more amino acids at its N-terminus.

Entrez Symbol:

MAP2K3

Uniprot Name:

MP2K3_HUMAN

Uniprot ID:

P46734

Data PDF:

CPM500

Specificity:

Recognizes both natural and recombinant Human MKK3

Host Species:

Rabbit

Immunogen:

Recombinant Full Length Human MKK3

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl of sterile, distilled water to the vial to fully solubilize the antibody to a concentration of 1 mg/ml.

Application:

WB

Application notes:

Western Blot, Immunoprepcipitation: 1:2000.

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.