Rabbit Anti-Human PAK1 pAb

Molecule:

PAK1

Synonyms:

PAK1, p21 (RAC1) activated kinase 1, PAKalpha

Species:

Human

Cat. No.:

CPP400 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Rabbit Anti-human PAK1 Polyclonal Antibody
Background: Human p21-GTPase activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NF-kB activation.

Entrez Symbol:

PAK1

Uniprot Name:

PAK1_HUMAN

Uniprot ID:

Q13153

Data PDF:

CPP400

Specificity:

Recognizes both natural and recombinant Human PAK1

Host Species:

Rabbit

Immunogen:

Recombinant Human PAK1 (a.a. 333-545)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl of sterile, distilled water to the vial to fully solubilize the antibody to a concentration of 1 mg/ml.

Application:

WB

Application notes:

Western blot: working dilution of 1:5,000

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.