Rabbit Anti-Mouse Akt1/PKB pAb

Molecule:

PKB/Akt

Synonyms:

Akt1, thymoma viral proto-oncogene 1, Akt, PKB, Rac, LTR-akt, PKB/Akt, PKBalpha

Species:

Mouse

Cat. No.:

CPA000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Rabbit Anti-Akt/PKB Polyclonal Antibody
Background: Akt (also termed PKB, or RAC (Related to PKA and PKC), is the cellular homologue of the viral oncoprotein v-Akt. Akt is a serine / threonine kinases that consist of an N-terminal PH domain, a kinase domain and a C-terminal domain similar to that of the PKC family. Akta contains 480 amino acids, and can be activated by receptor tyrosine kinases through the PI 3-kinase pathway. Akt has been shown to suppress apoptosis. Recent study suggests that Akt may also be part of the NF-kB activation pathway.

Entrez Symbol:

Akt1

Uniprot Name:

AKT1_MOUSE

Uniprot ID:

P31750

Data PDF:

CPA000

Specificity:

Recognizes both natural and recombinant Mouse Akt1

Host Species:

Rabbit

Immunogen:

Mouse Akt-alpha (a.a. 375- 479)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl of sterile, distilled water to the vial to fully solubilize the antibody to a concentration of 1 mg/ml.

Cross Reactivity:

1200

Application:

WB

Application notes:

Western blot: working dilution of 1:5,000

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.