Rabbit Anti-Mouse CXCL12/SDF-1 alpha pAb

Molecule:

SDF-1alpha

Synonyms:

CXCL12, PBSF, SDF-1a, SDF1A, SDF1, SCYB12, TLSF, TPAR1, SDF-1 alpha, SDF1 alpha, CXCL12a

Species:

Mouse

Cat. No.:

CPS000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

This polyclonal antibody recognizes mouse and rat CXCL12/SDF-1 alpha.
Background: Chemokine (C-X-C motif) Ligand 12 (CXCL12) is also known as Stromal Cell-Derived Factor 1 alpha (SDF-1 alpha) is a 70-amino acid chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of CXCL12 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. CXCL12/SDF1 has been shown to be chemotactic for lymphocytes. In addition, CXCL12/SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T-cells. CXCL12/SDF1 binding to CXCR4 inhibits HIV-1 entry.

Entrez Symbol:

Cxcl12

Uniprot Name:

SDF1_MOUSE

Uniprot ID:

P40224

Data PDF:

CPS000

Specificity:

Recognizes both natural and recombinant mouse SDF-1 alpha

Host Species:

Rabbit

Immunogen:

Recombinant Mouse SDF-1 alpha, a 70-amino acid CXC chemokine.
AA Sequence of Immunogen: 22-89 (full length mature)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/ml.

Cross Reactivity:

1440

Application:

IHC, WB

Application notes:

Western blot: working dilution of 1:1,000
Immunohistochemistry: working dilution of 1:100-1:500

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.