Rabbit Anti-Mouse MAP2K1/MEK1 pAb

Molecule:

MEK1

Synonyms:

Map2k1, mitogen-activated protein kinase kinase 1, Mek1, MEKK1, MAPKK1, Prkmk1

Species:

Mouse

Cat. No.:

CPM200 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$260.00 BUY

Description:

Rabbit Anti- Human MEK1 Polyclonal Antibody
Background: MEK1 is one of the MEKs that are upstream of the MAPK ERK1/2. MEK1 is a dual-specific protein kinase that phosphorylates ERK1/2 on both threonine and tyrosine residues in the sequence TEY. Phosphorylation of these residues dramatically activates ERK1/2, which then phosphorylate their downstream substrate. MEK1 contains 393 amino acids and has a calculated molecular weight of 43.47 kDa. MEK1 itself is regulated by phosphorylation by one of the MEK kinases.

Entrez Symbol:

Map2k1

Uniprot Name:

MP2K1_MOUSE

Uniprot ID:

P31938

Data PDF:

CPM200

Specificity:

Recognizes both natural and recombinant Mouse MEK1

Host Species:

Rabbit

Immunogen:

Recombinant mouse full-length MEK1

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl of sterile, distilled water to the vial to fully solubilize the antibody to a concentration of 1 mg/ml.

Cross Reactivity:

3354

Application:

WB

Application notes:

Western Blot: 1: 1,000
Immunprecipitation: 1:1,000

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.