Rabbit Anti-Rat MCP-1 pAb

Molecule:

MCP-1

Synonyms:

Monocyte Chemoattractant Protein 1, C-C motif chemokine ligand 2, Scya2, Sigje, MCP-1, Ccl2

Species:

Rat

Cat. No.:

CPM000 pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$280.00 BUY

Description:

The polyclonal antibody recognizes rat Chemokine (C-C motif) Ligand 2 (CCL2)/ Monocyte Chemoattractant Protein 1 (MCP-1).
Background: Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2/MCP-1 displays chemotactic activity for monocytes and basophils but not for neutrophils. It binds to chemokine receptors CCR2 and CCR4. MCP-1 is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli. Rat CCL2/ MCP1 contains 148-amino acids with a NH2-terminal 29 residue signal sequence. The 3

Entrez Symbol:

Ccl2

Uniprot Name:

CCL2_RAT

Uniprot ID:

P14844

Data PDF:

CPM000

Specificity:

Recognizes both natural and recombinant rat MCP-1/CCL2

Host Species:

Rabbit

Immunogen:

Recombinant Rat CCL2 / MCP-1 (expressed in E. coli), aa 24-148 (full length mature)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 0.5 ml H2O.

Cross Reactivity:

1255

Application:

IHC, NT, WB

Application notes:

Western blot: 1:2000
Immunohistochemistry: 1:200

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.