Rabbit Anti-Rat CXCL12/SDF-1 beta pAb

Molecule:

SDF-1beta

Synonyms:

Sdf1, SDF-1 gamma, Stromal cell-derived factor 1, chemokine (C-X-C motif) ligand 12, stromal cell-derived factor-1 gamma, IRH, PBSF, SDF1, SDF1b, SDF-1 beta, TLSF, TPAR1, SCYB12, CXCL12b

Species:

Rat

Cat. No.:

CPS001 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

This polyclonal antibody recognizes rat and mouse CXCL12/SDF-1 beta.
Background: SDF-1 beta (stromal cell-derived factor-beta), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T-cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.

Entrez Symbol:

Cxcl12

Data PDF:

CPS001

Specificity:

Recognizes both natural and recombinant rat SDF-1 beta

Host Species:

Rabbit

Immunogen:

Recombinant Mouse SDF-1 beta
AA Sequence of Immunogen: 22-93 (full length mature)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/ml.

Cross Reactivity:

1255

Application:

IHC, WB

Application notes:

Western blot: working dilution of 1:1,000
Immunoprecipitation: working dilution of 1:300-500
Immunohistochemistry: working dilution of 1:100-500

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.