Rabbit Anti-Rat MMP2 pAb, Azide free

Molecule:

MMP2

Synonyms:

Matrix Metalloproteinase 2, Collagenase Type IV-A, Neutrophil Gelatinase, CLG4, CLG4A, MMP-II, MONA, TBE-1, Mmp2

Species:

Rat

Cat. No.:

CPM600AF pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

Rabbit Anti-Rat Matrix Metallopeptidase 2 pAb, azide free
Background: The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP. MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.

Entrez Symbol:

Mmp2

Data PDF:

CPM600AF

Specificity:

Recognizes both natural and recombinant rat MMP2

Host Species:

Rabbit

Immunogen:

Recombinant Rat 72-kDa type IV collagenase, active (catalytic domain) , aa 115-447

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/ml.

Application:

WB

Application notes:

Western blot : 1:2000
Immunoprecipitation: 1:500

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.