Rabbit Anti-Rat PAI1/SERPINE1 pAb

Molecule:

PAI1

Synonyms:

PAI1A, Pai1, Pai1aa, Planh, RATPAI1A, Serpine1, serpin family E member 1

Species:

Rat

Cat. No.:

CPP000 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$280.00 BUY

Description:

The polyclonal antibody recognizes rat Plasminogen Activator Inihibitor Type 1 (PAI1), a protein originally cloned from human endothelial cell and rat hepatoma cell cDNA libraries. As a member of the Serpin family of serine protease inhibitors, PAI1 inhibits both Tssue-type Plasminogen Activator (tPA) and Urokinase-type Plasminogen Activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.

Entrez Symbol:

Serpine1

Uniprot Name:

PAI1_RAT

Uniprot ID:

P20961

Data PDF:

CPP000

Specificity:

Recognizes both natural and recombinant rat PAI1

Host Species:

Rabbit

Immunogen:

Recombinant Rat PAI1 expressed in E. coli, aa 1-402 (full length)

Isotype:

IgG

Conjugate:

Unconjugated

Formulation:

Lyphilized from 1xPBS

Purification:

Protein A Chromatography

Reconstitution:

Centrifuge vial prior to opening. Add 200 μl sterile distilled water to the vial to fully solubilize the antibody to a concentration of 1.0 mg/ml.

Application:

WB

Application notes:

Western blot: 1:1,000

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at at -20°C for up to 1 year. After reconstitution, the preparation is stable for up to one month at 2-8°C. For long term storage, freeze in working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles.