Recombinant Human BMP-2

Molecule:

BMP-2

Synonyms:

Bone morphogenetic protein-2, BMP2A, BDA

Species:

Human

Cat. No.:

CRB100A pdf (datasheet)

Quantity/Size:

2 μg

Price:

$135.00 BUY

Description:

Recombinant Human BMP-2 is a homodimer consisting of two 115 amino acid non-glycosylated polypeptde chains.
Background: Bone Morphogenetic Protein 2 is a member of the BMP family of proteins, which are important for the development of bone and cartilage. BMP-2 through 7 belong to the TGF-beta superfamily.BMP-2 is produced as a pre/pro-protein, which is proteolytically processed to generate each subunit of the disulfide-linked homodimer, BMPs signal through type I and type II receptor tyrosine kinases and through SMAD proteins.

Entrez Symbol:

BMP2

Data PDF:

CRB100

Source:

E. coli

Molecular Weight:

26 kDa

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA).

Purity:

>95% by SDS-PAGE and HPLC

Biological Activity:

As determined by inducing alkaline phosphatase production of mouse ATDC-5 cells: typically 0.3 - 1.0 µg/ml.

Specific Activity:

> 2.0 x 10e3 U/mg

Endotoxin Level:

<1 EU/μg of Recombinant Human BMP-2 as determined by kinetic LAL analysis.

Amino Acid Sequence:

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/ml. DO NOT VORTEX. Allow several minutes for complete reconstitution. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. Upon receipt, store desiccated at -20°C for up to 1 year. Upon reconstitution, the preparation is stable for up to one month at 2-8°C.