Recombinant Human CCL14/HCC-1

Molecule:

CCL14

Synonyms:

CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3

Species:

Human

Cat. No.:

CRH100A pdf (datasheet)

Quantity/Size:

2 μg

Price:

$190.00 BUY

Description:

Recombinant Human CCL14 is a single, non-glycosylated polypeptide chain containing 72 amino acids.
Background: HCC-1/CCL14 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver and bone marrow.

Entrez Symbol:

CCL14

Data PDF:

CRH100

Source:

E. coli

Molecular Weight:

~8.4 kDa

Formulation:

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl.

Purity:

>96% as determined by HPLC and SDS-PAGE analyses

Biological Activity:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml.

Endotoxin Level:

Less than 1EU/μg as determined by LAL method.

Amino Acid Sequence:

TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C.

Storage/Stability:

This lyophilized preparation is stable at 2-8°C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C.