Recombinant Human CCL14/HCC-1

Molecule:

CCL14

Synonyms:

HCC-1, CC-1, CC-3, CKb1, HCC-3, MCIF, NCC2, SCYA14, SCTL2, SY14

Species:

Human

Cat. No.:

CRH100C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,700.00 / Special Price: $1,640.00 BUY

Description:

Recombinant Human CCL14 is a single, non-glycosylated polypeptide chain containing 72 amino acids.
Background: HCC-1/CCL14 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver and bone marrow.

Entrez Symbol:

CCL14

Data PDF:

CRH100

Source:

E. coli

Molecular Weight:

~8.4 kDa

Formulation:

Lyophilized from a sterile filtered solution containing 20 mM PBS, pH 7.4 + 100 mM NaCl

Purity:

>96% as determined by HPLC and SDS-PAGE analyses

Biological Activity:

Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml.

Endotoxin Level:

Less than 1EU/μg as determined by LAL method.

Amino Acid Sequence:

TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

This lyophilized preparation is stable at 2-4°C, but should be kept desiccated at -20°C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4°C.