Recombinant Human FGF-18

Molecule:

FGF18

Synonyms:

FGF-18, ZFGF5

Species:

Human

Cat. No.:

CRF010B pdf (datasheet)

Quantity/Size:

25 μg

Price:

$235.00 BUY

Description:

Recombinant Human FGF-18 is a single, non-glycosylated polypeptide chain containing 181 amino acids. Background: Human FGF-18 is encoded by the FGF18 gene. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles of in embryo development. FGF-18

Entrez Symbol:

FGF18

Uniprot Name:

Fibroblast growth factor 18

Uniprot ID:

O76093

Data PDF:

CRF010

Source:

E. coli

Molecular Weight:

~21.1 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

Purity:

>97% by SDS-PAGE and HPLC analyses

Biological Activity:

Fully biologically active when compared to standard. The ED50 determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/ml.

Endotoxin Level:

<0.1 ng/�g

Amino Acid Sequence:

AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSRRIRPTHP A

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

This lyophilized preparation is stable at 2-4°C, but should be kept desiccated at -20°C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4°C. For maximal stability, apportion the reconstituted