Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. GM-CSF is a growth factor for granulocyte-macrophage, erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. GM-CSF has also been reported to have a functional role on non-hematopoietic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. GM-CSF is species specific and human GM-CSF has no biological effects on mouse cells.
Recombinant Human GM-CSF is a single non-glycosylated polypeptide chain containing 128 amino acids.
Toll Free 888-769-1246
All prices on this site are for orders shipping within the US and Canada.Prices are in US dollars.
These products are for laboratory research purposes only, not for any human or animal diagnostic or therapeutic use.
All site content © 2017 Cell Sciences, Inc.