Recombinant Human H-RAS G12V Mutant GST

Molecule:

HRAS

Synonyms:

C-BAS/HASοΩΫ, C-H-RASοΩΫ, C-HA-RAS1οΩΫ, CTLOοΩΫ, H-RASIDXοΩΫ, HAMSV1οΩΫ, RASH1οΩΫ, p21rasοΩΫ, HRAS

Species:

Human

Cat. No.:

CSI11667 pdf (datasheet)

Quantity/Size:

50 μg

Price:

$430.00 BUY

Description:

Harvey rat sarcoma viral oncogene homolog, H-Ras G12V mutant with N-terminal GST tag. Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation G12V leads to elimination of the intrinsic GTPase activity. H-Ras (G12V) is effective in activation of PI3K and PKB, whereas N-Ras and K-Ras are more potent towards MAP kinase. The GST-Tag facilitates the proteinοΩΫs application in typical GST pull-down assays.

Entrez Symbol:

HRAS

Data PDF:

CSI11667

Source:

E. coli

Physical State:

Liquid

Formulation:

Frozen liquid in 25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM MgCl2, and 5 mM οΩΫ-mercaptoethanol.

Purity:

>95% by SDS-PAGE.

Storage/Stability:

Stable for 1 year at -80οΩΫC. Avoid freeze / thaw cycles.