Recombinant Human KGF-1 is a single, non-glycosylated polypeptide chain containing 164 amino acids.
Background: Human KGF-1 also known as Fibroblast growth factor 7 (FGF-7), is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. KGF/FGF-7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.
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