Recombinant Human Parathyroid Hormone aa7-84/Nitrogen-15

Molecule:

PTH

Synonyms:

PTH1 , PTH

Species:

Human

Cat. No.:

CRH006C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$2,800.00 BUY

Description:

Recombinant Human Parathyroid Hormone is a single, non-glycosylated, 15N stable isotope labeled polypeptide chain containing 78 amino acids. Background:Parathyroid hormone (PTH) is a single polypeptide of 78 amino acids. It is a critical hormone in the regulation of Ca2+ homeostasis and secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low.

Entrez Symbol:

PTH

Data PDF:

CRH006

Source:

E. coli

Molecular Weight:

~8.9 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a 0.2 οΨΒm filtered, concentrated solution in PBS, pH 7.4.

Purity:

>97% by SDS-PAGE and HPLC analysis

Endotoxin Level:

< 0.1 EU/οΨΒg protein, as determined by LAL assay

Amino Acid Sequence:

LMHNLGKHLN SMERVEWLRK KLQDVHNFVA LGAPLAPRDA GSQRPRKKED NVLVESHEKS LGEADKADVN VLTKAKSQ

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

The lyophilized protein is stable at 2-8οΨΑC. Upon receipt, store desiccated at -20οΨΑC. After reconstitution, the preparation is stable for up to one week at 2-8οΨΑC. For maximal stability, apportion the reconstituted preparation into working aliquots an