Recombinant Human Soluble TRAILR2

Molecule:

TRAILR2/DR5

Synonyms:

Fas-like protein, TNF-related apoptosis-inducing ligand receptor 2, apoptosis inducing protein TRICK2A, 2B, apoptosis inducing receptor TRAIL-R2, cytotoxic TRAIL receptor-2, death domain containing receptor for TRAIL, Apo-2L, death receptor 5, p53-regulated DNA da

Species:

Human

Cat. No.:

CRT502B pdf (datasheet)

Quantity/Size:

50 μg

Price:

$235.00 BUY

Description:

Background: TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic death domain which can activate the cell's apoptotic machinery. These receptors are activated by binding to with

Entrez Symbol:

TNFRSF10B

Uniprot Name:

Tumor necrosis factor receptor superfamily member 10B

Uniprot ID:

O14763

Data PDF:

CRT502

Source:

E. coli

Molecular Weight:

14.9 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile filtered solution without additives.

Purity:

>98% by SDS-PAGE and HPLC analyses.

Biological Activity:

Determined by its inhibitory effect of IL-8 production in human PBMC by human sTRAIL/Apo2L. 50% inhibition (100 ng/ml of sTRAIL/Apo2L) was reached using a concentration of 1,000 ng/ml of sTRAIL Receptor-2.

Endotoxin Level:

<0.1 ng/�g

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in sterile ddH2O to a concentration of 0.1-1.0 mg/ml. The solution can then be further diluted in other aqueous buffers.

Storage/Stability:

Lyophilized protein is stable at -20℃C for ?2 years from date of receipt. After reconstitution, stable for 1 week at 2-4℃C. For long term storage, aliquot and store with a carrier protein at -20℃C. Avoid repeated freeze-thaw cycles.