Recombinant Human soluble VEGFR2/KDR (D1-7)

Molecule:

VEGFR2/KDR

Synonyms:

fetal liver kinase 1, fetal liver kinase-1, protein-tyrosine kinase receptor Flk-1, soluble VEGFR2, tyrosine kinase growth factor receptor, FLK1, CD309, VEGFR, VEGFR2

Species:

Human

Cat. No.:

CRF104C pdf (datasheet)

Quantity/Size:

1.0 mg

Description:

Background: Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression

Entrez Symbol:

KDR

Uniprot Name:

Vascular endothelial growth factor receptor 2

Uniprot ID:

P35968

EC number:

2.7.10.1

Data PDF:

CRF104

Source:

Insect cells

Molecular Weight:

116 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile filtered solution in 25 mM MES, pH 5.5 + 100 mM NaCl.

Purity:

>95% by SDS-PAGE analysis.

Biological Activity:

ED50: Typically 10.0 ng/ml (Determined by its ability to abolish the binding of iodinated VEGF to solid surfaces or cell surfaces).

Endotoxin Level:

<0.1 ng/�g

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in water or PBS to a concentration of ?100 ?g/ml. The solution can then be further diluted in other aqueous buffers.

Storage/Stability:

Lyophilized protein is stable at 2-4℃C for 2 days and at -20℃C to -80℃C for >6 months. Avoid repeated freeze-thaw cycles.