Recombinant Human WNT1

Molecule:

WNT-1

Synonyms:

INT1, Proto-oncogene Int-1 homolog

Species:

Human

Cat. No.:

CRW001C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$9,900.00 BUY

Description:

Background: Wnt-1 is a secreted protein that signals through the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the increased expres

Entrez Symbol:

WNT1

Uniprot Name:

Proto-oncogene Wnt-1

Uniprot ID:

P04628

Data PDF:

CRW001

Source:

E. coli

Molecular Weight:

38.4 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile filtered solution without additives.

Purity:

>98% by SDS-PAGE and HPLC analyses.

Biological Activity:

The expected ED50 for this effect is 1.5 - 2.5 ng/ml in the presence of 200 ng/ml of human BMP-2. (ED50 was determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells).

Endotoxin Level:

<0.1 ng/�g

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in sterile ddH2O to a concentration of 0.1-1.0 mg/ml. The solution can then be further diluted in other aqueous buffers.

Storage/Stability:

Lyophilized protein is preferably stored desiccated at <0℃C. After reconstitution, stable for 1 week at 2-4℃C. For long term storage, aliquot and store at -20℃C.