Recombinant Mouse GM-CSF/CSF2

Molecule:

CSF2

Synonyms:

Granulocyte macrophage colony stimulating factor, Colony stimulating factor 2 (granulocyte-macrophage), GM-CSF, GMCSF, CSF

Species:

Mouse

Cat. No.:

CRG101C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,900.00 / Special Price: $1,690.00 BUY

Description:

Recombinant mouse GM-CSF is a single chain polypeptide consisting of 125 amino acid residues.
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. It is produced by endothelial cells, monocytes, fibroblasts and T cells in response to a number of inflammatory mediators.

Entrez Symbol:

Csf2

Uniprot Name:

Granulocyte-macrophage colony-stimulating factor

Uniprot ID:

P01587

Data PDF:

CRG101

Source:

E. coli

Molecular Weight:

14.3 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile-filtered aqueous solution containing 10 mM acetic acid.

Purity:

>95% by SDS-PAGE

Biological Activity:

Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of mouse FDC-P1, < 50 pg/ml.

Endotoxin Level:

≤1 U/µg of protein by kinetic LAL analysis

Amino Acid Sequence:

MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/ml. DO NOT VORTEX. Allow several minutes for complete reconstitution. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

Lyophilized protein is stable at room temperature for shipping purposes. Store desiccated at -20°C on receipt. After reconstitution, stable for ≤1 month at 2-8°C. For long term, store aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.