Recombinant Mouse Leptin

Molecule:

Leptin

Synonyms:

ob, obese, obesity factor

Species:

Mouse

Cat. No.:

CRL301C pdf (datasheet)

Quantity/Size:

5 mg

Price:

$445.00 BUY

Description:

Background: A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores. Product:

Entrez Symbol:

Lep

Uniprot Name:

Leptin

Uniprot ID:

P41160

Data PDF:

CRL301

Source:

E. coli

Molecular Weight:

16 kDa

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile filtered concentrated (1 mg/ml) solution in 0.1% TFA.

Purity:

>95% by SDS-PAGE and HPLC analyses.

Biological Activity:

Biological activity of Mouse Leptin is performed in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5ug Leptin/gram body weight for a period of 14 days. Significant

Endotoxin Level:

<0.1 ng/�g

Amino Acid Sequence:

MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in sterile ddH2O to a concentration of ?0.1 mg/ml. The solution can then be further diluted in other aqueous buffers.

Storage/Stability:

Lyophilized protein is stable at room temperature for 3 weeks, but is preferably stored desiccated at -20℃C. After reconstitution, stable for 1 week at 2-4℃C. For long term storage, aliquot and store at -20℃C with a carrier protein (0.1%