Recombinant Mouse MDC/CCL22

Molecule:

CCL22

Synonyms:

DCBCK, ABCD-1, Scya22

Species:

Mouse

Cat. No.:

CRM102C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,700.00 / Special Price: $1,640.00 BUY

Description:

Recombinant Mouse CCL22/MDC is a single, non-glycosylated polypeptide chain containing 68 amino acids.

Background: CCL22/MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity.

Data PDF:

CRM102

Source:

E. coli

Molecular Weight:

~7.8 kDa

Formulation:

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.

Purity:

>97 % by SDS-PAGE and HPLC analyses.

Biological Activity:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human activated lymphocytes is in a concentration range of 10-100 ng/ml.

Endotoxin Level:

<1 EU/μg of recombinant mouse MDC/CCL22 as determined by LAL method.

Amino Acid Sequence:

GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS

Reconstitution:

Centrifuge vial prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be divided into working aliquots and stored at -80°C. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

This lyophilized preparation is stable for several weeks at 2-4°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-4°C. For maximal stability, divide the reconstituted preparation into working aliquots and store at -80°C. Avoid repeated freeze-thaw cycles.