Recombinant Mouse Soluble RANK Ligand

Molecule:

RANKL

Synonyms:

ODF, OPGL, sOdf, CD254, OPTB2, RANKL, TRANCE, hRANKL2, soluble Receptor Activator of NFkB Ligand, TNF-related activation-induced cytokine, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kapp

Species:

Mouse

Cat. No.:

CRR101D pdf (datasheet)

Quantity/Size:

100 μg

Price:

$640.00 BUY

Description:

Recombinant mouse soluble RANK Ligand is a non-glycosylated protein, containing 174 amino acids. Background: Receptor Activator of NF-?B Ligand (RANK Ligand) is a cell-bound marker (CD254) related to the TNF family of proteins. RANK Ligand plays a critical role in bone metabolism, particularly osteoclast differentiation. In addition, RANK Ligand is expressed by some T cells is thought to promote dendritic cell maturation.

Entrez Symbol:

TNFSF11

Data PDF:

CRR101D

Source:

E. coli

Molecular Weight:

19.9 kDa

Physical State:

Lyophilized

Formulation:

Sterile filtered and lyophilized from 10 mM Na2PO4, pH 7.5 + 50 mM NaCl.

Purity:

Err:509

Biological Activity:

The activity is measured by its ability to induce osteoclast formation on mouse RAW264.7 cells using a concentration of 50 ng/mL.

Endotoxin Level:

0.22 EU/οΨΒg protein (with a 50% confidence range), as measured by kinetic LAL analysis

Amino Acid Sequence:

PAMMEDSWLD VAQRGKPAEQ PFAHLTINAA SIPSGSHKVT LSSWYHDRGW AKISNMTLSN GKLRVNQDGF YYLYANICFR HHETSGSVPT DYLQLMVYVV KTSIKIPSSH NLMKGGSTKN WSGNSEFHFY SINVGGFFKL RAGEEISIQV SNPSLLDPDQ DATYFGAFKV QDID

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to the vial to fully solubilize the protein to a concentration of 0.1 mg/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.

Storage/Stability:

Lyophilized product is very stable at -20οΨΑC. Reconstituted material should be aliquoted and frozen at -20οΨΑC. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Please note that the addition of any carrier protei