Sheep Anti-Human tPA pAb

Molecule:

tPA

Synonyms:

tPA , PLAT , T-PA , TPA

Species:

Human

Cat. No.:

CS257A pdf (datasheet)

Quantity/Size:

100 μg

Price:

$640.00 BUY

Concentration:

3.9 mg/ml

Description:

Sheep Anti-human tPA polyclonal antibody. Background: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Entrez Symbol:

PLAT

Uniprot ID:

P00750

Data PDF:

CS257

Specificity:

Human tPA

Host Species:

Sheep

Immunogen:

Recombinant full length wild-type human tPA

Isotype:

IgG

Formulation:

Liquid in 0.05M Sodium Phosphate + 0.1M NaCl + 1mM EDTA, pH 6.6

Purification:

Affinity purified by immobilized human tPA

Storage/Stability:

After first thaw, store in working aliquots at -80οΨΑC. Avoid repeated freeze-thaw cycles.