EDNRA encodes the bovine protein Endothelin-1 receptor (ETA), a peptide that plays a role in potent and long-lasting vasoconstriction. The ETA receptor is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETB. They are located primarily in the vascular smooth muscle where they play a role in vasoconstriction and cell proliferation.

The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.