Corn Trypsin Inhibitor

Synonyms:

Trypsin/factor XIIA inhibitor, Hageman factor inhibitor, CHF1

Cat. No.:

CRT186B pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$250.00 BUY

Description:

Corn Trypsin Inhibitor (CTI) is a highly specific inhibitor of trypsin and Factor XIIa that does not affect Factors VIIa, IXa, Xa, or thrombin. CTI forms a one-to-one molar complex with target proteases and is useful for distinguishing between the intrinsic and extrinsic coagulation cascades. CTI is extracted from high quality sweet corn meal into a physiologic buffer then purified by a combination of gel filtration, ion-exchange, and affinity chromatography. The final CTI preparation appears as a single band by SDS-PAGE analysis under both reducing and non-reducing conditions. Preparations of CTI are tested for the ability to prolong the aPTT assay without affecting the PT assay.

Concentration:

> 1 mg/ml, lot specific

Entrez Symbol:

CHF1

Uniprot Name:

Trypsin/factor XIIA inhibitor

Uniprot ID:

P01088

Data PDF:

CRT186

Molecular Weight:

12.5 kDa

Physical State:

Liquid

Formulation:

20 mM Tris-HCl, 0.15 M NaCl, pH 7.4

Purity:

> 95% by SDS-PAGE analysis

Specific Activity:

>10 U/mg, 1 unit is defined as the amount of CTI required to double the aPTT of normal human plasma.

Storage/Stability:

Store at -80°C