Recombinant Human Vitronectin

Molecule:

Vitronectin

Synonyms:

V75, VN, VNT, VTN S-protein, Somatomedin-B

Species:

Human

Cat. No.:

CRH116B pdf (datasheet)

Quantity/Size:

10 μg

Price:

$300.00 BUY

Description:

Vitronectin (VTN) which is a part of the pexin family is a cell adhesion and spreading factor found in serum and tissues. VTN interacts with glycosaminoglycans and proteoglycans. VTN inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to numerous serpin serine protease inhibitors. An over expression of VTN, integrins and plasminogen in migrating cells has been observed during wound healing. Human Recombinant vitronectin, produced in E.coli, is a single, non-glycosylated polypeptide chain containing 482 amino acids (20-478 a.a) fused to a 23 amino acid His-tag at the N-terminus.

Concentration:

0.5 mg/ml

Entrez Symbol:

VTN

Uniprot ID:

P04004

Source:

E. coli

Molecular Weight:

54.7 kDa

Tag:

His

Physical State:

Liquid

Formulation:

20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.

Purity:

>90% by SDS-PAGE.

Amino Acid Sequence:

MGSSHHHHHH SSGLVPRGSH MGSDQESCKG RCTEGFNVDK KCQCDELCSY YQSCCTDYTA ECKPQVTRGD VFTMPEDEYT VYDDGEEKNN ATVHEQVGGP SLTSDLQAQS KGNPEQTPVL KPEEEAPAPE VGASKPEGID SRPETLHPGR PQPPAEEELC SGKPFDAFTD LKNGSLFAFR GQYCYELDEK AVRPGYPKLI RDVWGIEGPI DAAFTRINCQ GKTYLFKGSQ YWRFEDGVLD PDYPRNISDG FDGIPDNVDA ALALPAHSYS GRERVYFFKG KQYWEYQFQH QPSQEECEGS SLSAVFEHFA MMQRDSWEDI FELLFWGRTS AGTRQPQFIS RDWHGVPGQV DAAMAGRIYI SGMAPRPSLA KKQRFRHRNR KGYRSQRGHS RGRNQNSRRP SRATWLSLFS SEESNLGANN YDDYRMDWLV PATCEPIQSV FFFSGDKYYR VNLRTRRVDT VDPPYPRSIA QYWLGCPAPG HL

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.