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HTR3A is one of the several different ligand-gated ion channel receptors for 5- hydroxytrptamine (serotonin), a biogenic hormone that functions as a hormone, a neurotransmitter, and a mitogen. It is a cation-specific, but otherwise relatively nonselective ion channel that, when activated, causes fast depolarizing responses in neurons.
The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.