Human 5-Hydroxytryptamine 2A Receptor



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CSH1006MP pdf (datasheet)


10 mg


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The serotonin 2A receptor (or 5-HT2A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). The 5HT2A receptor is a G protein-linked receptor that is the main excitatory receptor subtype among the GPCRs for serotonin, although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbitofrontal cortex. This receptor was first noted for its importance as a target of serotonergic psychedelic drugs such as LSD. 5-HT2A may be a necessary receptor for the spread of the human polyoma virus called the JC virus. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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