Human C-C Chemokine Receptor Type 4

Synonyms:

CD194, CC-CKR-4, CKR4, CMKBR4

Cat. No.:

CSH3039MP pdf (datasheet)

Quantity/Size:

10 mg

Price:

$1,695.00 BUY

Description:

Chemokines and their receptors, which mediate signal transduction, are critical for the recruitment of effector immune cells to the site of inflammation. CCR4 is a G protein coupled receptor that binds the following CC chemokines: CCL2 (MCP-1), CCL4 (MIP -1), CCL5 (RANTES), CCL17 (TARC), and CCL22 (Macrophage-derived chemokine). CCR4 is selectively expressed by T cell subsets such as Th2 cells, skin-homing memory/effector T cells, and regulatory T cells. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P51679

Data PDF:

CSH3039