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Chemokines and their receptors, which mediate signal transduction, are critical for the recruitment of effector immune cells to the site of inflammation. CCR6 is a G protein coupled receptor that bindsmacrophage inflammatory protein 3 alpha (MIP-3 alpha) and appears to play a role in regulating the migration and recruitment of dendritic and T cells during inflammatory and immunological responses.
The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.