Human C-C Chemokine Receptor Type 7

Synonyms:

CD197, CDw197, BLR2, CC-CKR-7, CMKBR7, EBI1

Cat. No.:

CSH1145MP pdf (datasheet)

Quantity/Size:

10 mg

Price:

$1,695.00 BUY

Description:

Chemokines and their receptors, which mediate signal transduction, are critical for the recruitment of effector immune cells to the site of inflammation. CCR7 is a G protein coupled receptor and wo ligands have been identified for CCR7: the chemokines (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21). CCR7 is expressed in various lymphoid tissues and activates B and T lymphocytes. CCR7 has been shown to stimulate dendritic cell maturation. CCR7 is also involved in homing of T cells to various secondary lymphoid organs. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P32248

Data PDF:

CSH1145