Human C5a anaphylatoxin chemotactic receptor 2


Complement Component 5a Receptor 2, G Protein-Coupled Receptor 77, GPF77, G Protein-Coupled Receptor C5L2, C5L2

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CSH3044PR pdf (datasheet)


50 µg


$8,780.00 BUY


C5AR2 encodes the G protein-coupled receptor for the C5a anaphylatoxin peptide known as C5a anaphylatoxin chemotactic receptor 2. This receptor is involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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