Human Coagulation Factor XIIIa

Molecule:

Factor XIIIa

Synonyms:

Coagulation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain

Species:

Human

Cat. No.:

CSI20180A pdf (datasheet)

Quantity/Size:

250 μg

Description:

Human Factor XIIIa is activated from Factor XIII by cleavage with human alpha thrombin. The thrombin is subsequently removed via chromatography. Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis. This product is our IVD grade. Please inquire about our High Purity grade product.

Concentration:

> 2.0 mg/ml

Entrez Symbol:

F13A1

Uniprot Name:

Coagulation factor XIIIa

Uniprot ID:

P00488

EC number:

2.3.2.13

Data PDF:

CSI20180

Source:

Human plasma

Molecular Weight:

312 kDa

Physical State:

Liquid

Formulation:

20 mM HEPES, 150 mM NaCl, 0.5 mM EDTA, 0.1% Mannitol (w/v), pH 7.4

Specific Activity:

> 20 PEU/mg, 1 PEU (plasma equivalent unit) = Factor XIIIa activity in 1 ml of normal human plasma.

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.