Human fMet-Leu-Phe receptor


FMLP, Formyl Peptide Receptor 1, N-Formylpeptide Chemoattractant Receptor, FMLP Receptor

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CSH3092MP pdf (datasheet)


10 mg


$1,695.00 BUY


FPR1 encodes the cell surface receptor protein fMet-Leu-Phe, a G protein-coupled receptor 1 family protein that binds and is activated by N-Formylmethionine-containing oligopeptides, particularly N-Formylmethionine-leucyl-phenylalanine (FMLP). The formyl peptide receptor family, FPR1, FPR2 and FPR3 are Gi-protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes. FPRs are involved in antibacterial host defense and inflammation. FPR1 is prominently expressed by mammalian phagocytic cells where it mediates cellular responses to the Nformylmethionine-containing oligopeptides released by invading microorganisms and injured tissues. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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