Human Free fatty acid receptor 2


FFA2, FFA2R, G-Protein Coupled Receptor 43, GPR43

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CSH3062PR pdf (datasheet)


50 µg


$8,780.00 BUY


FFAR2 encodes a protein known as Free fatty acid receptor 2, a class A G-protein coupled receptor that is a member of the GP40 family of receptors that are clustered together on chromosome 19. Free Fatty Acid receptors are a group of Gq/11 proteincoupled receptors currently classified into FFA1, FFA2, FFA3 and FFA4 subtypes. These receptors are concentrated in pancreatic islet cells, immune cells and in the brain and are important in immunity and metabolism. FFA2 is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. It is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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