Human G-protein coupled receptor 84


G Protein-Coupled Receptor 84, Inflammation-Related G Protein-Coupled Receptor EX33, GPCR4

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CSH2135MP pdf (datasheet)


10 µg


$1,695.00 BUY


GPR84 encodes the G-protein coupled receptor 84, a receptor for medium-chain free fatty acid (FFAs) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. This receptor is not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. GPR84 may have an important role in processes from fatty acid metabolism to regulation of the immune system. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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