Human Gonadotropin-releasing hormone receptor

Synonyms:

GnRH receptor, GnRH-R, Leutinizing Hormone Releasing Horomone Receptor, LRHR, Luliberin Receptor

Cat. No.:

CSH3068PR pdf (datasheet)

Quantity/Size:

50 µg

Price:

$8,780.00 BUY

Description:

GNRHR encodes the protein known as Gonadotropin-releasing hormone receptor (GnRH). GnRH receptors are a group of Gq/11-protein-coupled receptors that are divided into two subtypes; GnRH and GnRH2. GnRH2 is silenced in humans. GnRH is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P30968

Data PDF:

CSH3068