Human Gonadotropin-releasing hormone receptor


GnRH receptor, GnRH-R, Leutinizing Hormone Releasing Horomone Receptor, LRHR, Luliberin Receptor

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CSH3068MP pdf (datasheet)


10 mg


$1,695.00 BUY


GNRHR encodes the protein known as Gonadotropin-releasing hormone receptor (GnRH). GnRH receptors are a group of Gq/11-protein-coupled receptors that are divided into two subtypes; GnRH and GnRH2. GnRH2 is silenced in humans. GnRH is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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