Human Histamine H1 Receptor

Synonyms:

H1R, HH1R, Histamine Receptor, Subclass H1

Cat. No.:

CSH4125PR pdf (datasheet)

Quantity/Size:

50 µg

Price:

$8,780.00 BUY

Description:

HRH1 encodes the protein known as Histamine H1 Receptor, a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. Histamine H1 receptors mediate allergic responses. This receptor is activated by the biogenic amine histamine, a ubiquitous messenger molecule released from mast cells, enterochromaffinlike cells, and neurons. The actions of histamine are mediated by histamine receptors H1, H2, H3 and H4. Histamine H1 Receptor is expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous system. The H1 receptor is linked to an intracellular G-protein (Gq) that activates phospholipase C and the inositol triphosphate signalling pathway. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P35367

Data PDF:

CSH4125