Human Neuropeptide Y receptor type 1

Synonyms:

Neuropeptide Y Receptor Y1, NPY1-R, NPYY1

Cat. No.:

CSH1079PR pdf (datasheet)

Quantity/Size:

50 µg

Price:

$8,780.00 BUY

Description:

NPY1R encodes the protein known as Neuropeptide Y receptor type 1. Neuropeptide Y (NPY) receptors are a family of Gi/o-protein-coupled receptors that are currently divided into four subtypes: Y1, Y2, Y4 and Y5. These receptors mediate a diverse range of biological actions including stimulation of food intake and modulation of circadian rhythm. The neuropeptide Y receptor type 1 mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of neuropeptide Y receptor type 1 may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P25929

Data PDF:

CSH1079