Human Neuropeptide Y receptor type 1


Neuropeptide Y Receptor Y1, NPY1-R, NPYY1

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CSH1079MP pdf (datasheet)


10 mg


$1,695.00 BUY


NPY1R encodes the protein known as Neuropeptide Y receptor type 1. Neuropeptide Y (NPY) receptors are a family of Gi/o-protein-coupled receptors that are currently divided into four subtypes: Y1, Y2, Y4 and Y5. These receptors mediate a diverse range of biological actions including stimulation of food intake and modulation of circadian rhythm. The neuropeptide Y receptor type 1 mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of neuropeptide Y receptor type 1 may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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