Human Proteinase-activated receptor 2


F2R Like Trypsin Receptor 1, PAR2, Coagulation factor II receptor-like 1, Thrombin receptor-like 1, GPR11

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CSH2062PR pdf (datasheet)


50 µg


$8,780.00 BUY


F2RL1 encodes proteinase-activated receptor 2, a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G proteincoupled cell surface receptor family. Proteinase-activated receptor 2 is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. Proteinase-activated receptor 2 modulates inflammatory responses, obesity, metabolism, and acts as a sensor for proteolytic enzymes generated during infection. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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