Human Type-1 Angiotensin Receptor

Synonyms:

AG2S, AT1, AT1BR, HAT1R

Cat. No.:

CSH1028MP pdf (datasheet)

Quantity/Size:

10 mg

Price:

$1,695.00 BUY

Description:

Angiotensin II receptor type 1 is the best characterized angiotensin receptor. It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to Gq/11 and thus activates phospholipase C and increases the cytosolic Ca2+ concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P30556

Data PDF:

CSH1028