Human Vasopressin V1b Receptor


Arginine Vasopressin Receptor 1B, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, VPR3

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CSH1103PR pdf (datasheet)


50 µg


$8,780.00 BUY


Human Arginine Vasopressin Receptor V1B (AVPR1B) is one of the three major receptor types for vasopressin (AVPR1A and AVPR2 being the others). The activity of this receptor is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

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